LONDON — For three years, Connie McPherson had debilitating leg ulcers that were so painful she sometimes couldn’t sleep. Despite repeated surgery, antibiotics, steroids and other treatments, nothing helped.
Then last year, she took part in a trial for a new gel aimed at chronic wounds.
“It was the answer to my prayers,” said McPherson, 58, a real estate agent in Tulsa, Oklahoma. Within weeks, McPherson said the ulcer treated was completely healed. “I tried everything possible and this is the only thing that worked.”
The gel used to treat McPherson was developed by a team led by David Becker, a professor of cell and developmental biology at University College London. The gel, named Nexagon, works by interrupting how cells communicate and prevents the production of a protein that blocks healing. That allows cells to move faster to the wound to begin healing it.
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